Capture large biological volumes without losing the 3D context of the sample.
Reduce setup effort with automated calibration and chromatic correction.
Move from organoid arrays to whole-animal imaging within the same system.
Automated acquisition and processing help move more samples through the workflow.
From organoid arrays to whole-animal specimens, UL combines scale, automation and flexible imaging modes in one system.
All scales
Large-volume imaging of cleared organs and tissues for structural, cellular and spatial analysis
Explore organoids in 3D, from overall structure to cellular detail.
Visualize whole specimens across developmental stages to study morphology, growth and tissue organization
Visualize tumor burden and compound distribution across whole cleared specimens
Image intact cleared animals to preserve spatial context across organs and systems
A large-volume workflow demonstrated on a 30 × 86 × 18 mm whole-mouse sample using a 5× objective
49 x 90 x 40 mm
Maximum sample size
2.5x 2.5 x 2.5 mm
Single field of view
2.6 × 2.6 × 10 µm
Acquired voxel size
SpecificationsConfirmed UL parameters. Resolution is objective- and application-dependent.
Standard objectives
Sample handlingMaximum sample volume
System alignment & calibration
Typical sample type
Illumination beams
Flip imaging for extra large samples
System objectives
Processing workflow
49x90x40mm (with flip z)
Automatic calibration and chromatic correction
Organoids to whole-animal imaging
Single- and double-side excitation
Flip imaging supported
2× / 5× / 10× / 25×
Acquisition, processing and large-volume data workflow through LiT through LiTScan software
Maximum volume varies by platform
Level of automation varies by system
Often optimized for narrower sample ranges
Configuration varies by platform
Multi-orientation workflows vary
Objective range varies by platform
Often distributed across separate tools
Installation, setup and system training.
Clearing, mounting and acquisition support.
Processing and analysis support.
